0.1M Sodium Nitrate Preparation and Standardization

0.1M Sodium Nitrate Preparation and Standardization of volumetric solution as per USP:

Preparation of 0.1M Sodium Nitrate:

  • Take 1000ml of volumetric flask or bottle.
  • Add 6.9g of sodium nitrate into it.
  • Dissolve the sodium nitrate in sufficient water and dilute up to 1000lml of water.

Standardization of 0.1M Sodium Nitrate:

  • Dry the USP Sulfanilamine RS at 105°C for 3hrs.
  • Weigh about 500mg/0.5g of USP Sulfanilamine RS.
  • Transfer into the suitable beaker.
  • Add 20ml of hydrochloric acid and 50ml of water.
  • Stir the solution until dissolved and cool to 15°C.
  • Maintaining temperature at about 15°C, titrate slowly with sodium nitrate solution.
  • Determine the end-point electrometrically, using a platinum-calomel electrode or platinum-platinum electrode.

17.22mg of sulfanilamide is equivalent to 1ml of 0.1M sodium nitrate.

Calculation formula of 0.1M Sodium Nitrate:

Molarity of Sodium Nitrate = W / 172.2 x V

0.1M Sodium Nitrate Preparation
0.1M Sodium Nitrate Preparation

Safety Instructions of Sodium Nitrate:

  • Sodium Nitrate is very hazardous in case of eye contact (Irritant), ingestion, or inhalation.
  • Hazardous in case of skin contact.
  • Prolonged exposure may result in skin burns and ulcerations.
  • Overexposure by inhalation may cause respiratory irritation.
  • Severe over-exposure can result in death.
  • Inflammation of the eye is characterized by redness, watering, and itching.

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1 thought on “0.1M Sodium Nitrate Preparation and Standardization”

  1. Thanks for sharing, i have a question, what is the principle of the platinum-platinum electrode? is there a redox reaction?

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