Dissolution Apparatus Do's And Don'ts In Pharma

Dissolution Apparatus Do’s And Don’ts:

Dissolution apparatus do’s and don’ts will help to improve the performance of the apparatus for a long period of time.

Dissolution Do’s:

Before using the equipment; verify that the equipment calibration and performance verification status is within the validity period.
Verify the depth of the paddle/Basket by using calibrated Depth Gauge during calibration.
The water bath should be filled up to the mark Water level without jar with purified water.
External probe should be handled with care.
Verify that the tube from the inlet and outlet of temperature controller unit is connected to the inlet and outlet of the bath respectively.
Check for the knob of top plate and the jar locking, loose knob or wrongly placed top plate will affect the centering and the paddle to the jar bottom height.
When paddles/baskets are used with corrosive materials such as hydrochloric acid or media containing salts; immediately after each use rinse them with purified water.

Dissolution Don’ts:

Do not start the heater, if there is no water in the tank upto the mark level.
Do not hold the stirrer hood while in operation.
Do not force the paddle while inserting. This might increase the wobble in the paddle.

Dissolution apparatus do’s and don’ts in pharmaceuticals is a precautionary measure for apparatus.

Also Read:

For interview preparation refer